National Institute of Plant Genome Research
Digital India   Azadi Ka Amrit Mahotsav     
    Dr. Divya Mishra
    Staff Scientist II,
    National Institute of Plant Genome Research (NIPGR), New Delhi
    Lab No.:  104
    E-mail: ;
    Social Platforms: LinkedIn, ResearchGate, Twitter
 Professional & Academic Background:
August 2023-Present: Scientist II, National Institute for Plant Genome Research (NIPGR)
2022-2023: Post-Doctoral Fellow, University of Wisconsin-Madison|OteguiLab,Wisconsin, USA.
2020-2022: : Post-Doctoral Fellow, Kansas State University, Kansas, USA.
2013-2019: Ph.D. student, National Institute of Plant Genome Research, New Delhi, India
2011-2013: MSc-Lifesciences, School of Lifesciences, Jawaharlal Nehru University, New Delhi, India
2009-2011: B.Sc., Chhatrapati Shahu Ji Maharaj University, Kanpur, India
 Awards and Honors :
2023: Early Career Plant Scientist Travel Award and Oral Presentation in ASPB Plant Biology,Savanhh
2022-2024: Early Career Representative (ECR),-American Society of Plant Biologist
2021-2023: Assistant Feature Editor, Plant Physiology, ASPB
2023-2024: Spotlight Editor, Physiologia Plantarum
2023-2025: Early Career Professional Representative (ECLP), Genetics Society of America
2014, 2016: Best poster awardee at the prestigious proteomics international conferences, 'PSI-2014' and 'PSIAOAPO-2016' organized by the Proteomic Society of India.
2013: Junior Research Fellowship and Lectureship in National Eligibility Test (NET) in Life Sciences, India.
2013: Graduate Aptitude Test in Engineering (GATE), in Life Sciences, India.
 Research Interests

High-temperature stress (HTS) has been recognized as a significant threat to agriculture, posing a serious challenge to global food security. The increasing earth's surface temperature at an unprecedented rate is an alarming signal for meeting current and future global challenges. HTS mediated negative changes not only affect the health and economic condition of the Indian population but also influence global food security and create an imbalance in the carbon cycle. Therefore, it is necessary to understand the high-temperature mediated alterations in the developmental processes.

Research Question: How does HTS affect nitrogen fixation?

Legumes can form symbiotic associations with rhizobia initiated by exchanging molecular signals and activating a unique plant signaling pathway called the "common symbiosis pathway". Legumes exposed to heat stress during the reproductive phase experience sugar starvation, leading to aborted flowers, sterile pollen and ovule, impaired fertilization, decreased seed filling, smaller-sized seeds, and depleted yields (Liu et al., 2019; Sita et al., 2017). The rhizobia fixing nitrogen for the legumes demands carbon sources for its energy needs. Therefore, under heat stress, the plant has to decide where to divert its energy: (i) towards nitrogen fixation or (ii) to reproductive development and yield. As global climate changes bring about unexpected heat stress episodes, it is becoming necessary to investigate this question and be ready for the future with engineered crops producing better yields.

Research Question: How does HTS affect the grain/seed yield of crops?

The grain quality and quantity are determined by the photoassimilate reserve in the source and sink capacity to store the assimilates (Abdelrahman et al., 2019). Carbohydrate partitioning between the source (such as leaves and stems) and sink (spikelet and grain) is negatively affected under stress conditions, which is crucial for overall growth and development and grain quality (Saddhe et al., 2021). Autophagy is essential for nutrient remobilization from source to sink organs. We will explore the interaction of autophagy with starch and N remobilization during grain filling under HTS.

 Group Members


Mishra, D. and Otegui, M.S. (2023) Autophagy in crop plants: A long way to go! Autophagy Reports. (In press)
Mishra, D#. (2023) How pink is too pink: A tussle between plant and nature. Physiologia Plantarum,175(2), e13895, (# corresponding author)
Mishra, D#. (2023) Closing the Loop: Three Musketeers of Autophagy-ATG2, ATG18a, and ATG9. Plant Physiology, 2022, kiac416 corresponding author)
Mishra, D#. (2023) Off-putting! No red, no ripe: Methylglyoxal inhibits fruit ripening. Plant physiology, kiad239. corresponding author)
Mishra, D#. (2023) Hero or sidekick? Organellar reactive oxygen species during abscisic acid-induced stomatal closure, Plant Physiology kiad080, corresponding author)
Pandey A, Sharma P, Mishra D*, Dey S, Malviya R, Gayen D. (2023) Genome-wide identification of the fibrillin gene family in chickpea (Cicer arietinum L.) and its response to drought stress. International Journal of Biological Macromolecules, 234, 123757.* Co-first author)
Kaur, G.; Mishra, D#. (2022) AtABCG14: A Long-Distance Root-to-Shoot Carrier of Cytokinin. Int. J. Plant Biol., 13, 352-355. (# corresponding author)
Mishra, D# (2022) Take it easy in the heat: Transcription factors PIF4 and TCP4 interplay to slow leaf growth, Plant Physiology, kiac416, corresponding author)
Mishra, D# (2022) A big role for a microRNA in regulating cold tolerance and hormone signaling in rice, Plant Physiology, kiac292, corresponding author)
Mishra, D# (2022) How Stripe Rust Overcomes Wheat's Defenses, Plant Physiology.kiac183, corresponding author)
Sharma, V.K., Marla, S., Zheng, W. Mishra, D., Huang, J., Zhang, W., Morris, GP., Cook DE. CRISPR guides induce gene silencing in plants in the absence of Cas. Genome Biol 23, 6 .
Mishra, D., Shekhar, S., Chakraborty, S., Chakraborty, N. (2021). Wheat 2-Cys peroxiredoxin plays a dual role in chlorophyll biosynthesis and adaptation to high temperatures. Plant J. 105,1374-1389.
Mishra, D., Shekhar, S., Chakraborty, S., Chakraborty, N. (2021). High temperature stress responses and wheat: Impacts and alleviation strategies. Environmental and Experimental Botany, 190, 104589.
Mishra, D., Suri, G.S., Kaur, G., Tiwari, M., (2021). Comprehensive analysis of structural, functional, and evolutionary dynamics of Leucine Rich Repeats-RLKs in Thinopyrum elongatum. International Journal of Biological Macromolecules,183, 513-527.
Pareek A., Mishra, D., Shekhar, S., Chakraborty, S., & Chakraborty, N. (2021). The small heat shock proteins,chaperonin 10, in plants: An evolutionary view and emerging functional diversity. Environmental and Experimental Botany, 182, 0432.
Alsaber, A, Al-Herz, A, Pan, J, AL-Sultan, AT, Mishra, D; KRRD Group. (2021). Handling missing data in a rheumatoid arthritis registry using random forest approach. International Journal of Rheumatic Diseases 24,1282-1293
Mishra, D., Suri GS, Kaur G, Tiwari M. (2021). Comparative insight into the genomic landscape of SARS-CoV-2 and identification of mutations associated with the origin of infection and diversity. Journal of Medical Virology 93, 2406-2419.
Tiwari, M., and Mishra, D#. (2020) Investigating the genomic landscape of novel coronavirus (2019-nCoV) to identify non-synonymous mutations for use in diagnosis and drug design. Journal of Clinical Virology,128,1044. author and corresponding author)
Pareek A., Rathi D., Mishra D., Shekhar S., Chakraborty S., & Chakraborty N. (2019).Physiological plasticity to high temperature stress in chickpea: Adaptive responses and variable tolerance. Plant Sciences, 289, 110258.
Mishra, D., Shekhar, S., Chakraborty, S., & Chakraborty, N. (2018). Carboxylate clamp tetratricopeptide repeat (TPR) domain containing Hsp90 cochaperones in Triticeace: An insight into structural and functional diversification. Environmental and Experimental Botany, 155, 31-44.
Mishra, D., Shekhar S., Chakraborty S., Chakraborty N. (2017). Cultivar-specific high temperature stress responses in bread wheat (Triticum aestivum L.) associated withphysicochemical traits and defense pathways. Food Chemistry, 221, 1077-1087.
Shekhar, S., Agrawal, L., Mishra, D., Buragohain, A. K., Unnikrishnan, M., Mohan, C., et al. (2016). Ectopic expression of amaranth seed storage albumin modulates photoassimilate transport and nutrient acquisition in sweetpotato. Scientific Reports, 6, 25384.
Shekhar, S., Mishra, D., Gayali, S., Buragohain, A. K., Chakraborty, S., & Chakraborty, N. (2016). Comparison of proteomic and metabolomic profiles of two contrasting ecotypes of sweetpotato (Ipomoea batata L.). Journal of Proteomics,143, 306-317.
Shekhar, S., Mishra, D., Buragohain, A. K., Chakraborty, S., & Chakraborty, N. (2015).Comparative analysis of phytochemicals and nutrient availability in two contrasting sweet potato cultivars (Ipomoea batatas L.). Food Chemistry, 173, 957-965.

 Book Chapter

Mishra D., Shekhar S., Singh D., Chakraborty S., Chakraborty N. (2018) Heat Shock Proteins and Abiotic Stress Tolerance in Plants. In: Asea A., Kaur P. (eds) Regulation of Heat Shock Protein Responses. Heat Shock Proteins, vol 13. Springer, Cham.
Mishra, D., Suri GS, Kaur G, Mehta S, Singh B, Tiwari M (2021). Genomic Evidence Provides the Understanding of SARS-CoV-2 Composition, Divergence, and Diagnosis. Integrated Omics Approaches Infectious Diseases, 542, Springer Nature.

 Editorial experience

Academic Editor, Plant Direct.
Editorial Board Member, Crop Design, Elsevier.
Early Career Reviewer, The Journal of Biological Chemistry.
Served as a social media editor, Crop Science, American Society of Crop Science.
Review editor, Frontiers in plant sciences and pharmaceutical innovations.
Reviewer Board Member, Microorganisms.
Serving as a reviewer in evaluating several research works | Web of Science.