Profile
Research Interests
High-temperature stress (HTS) has been recognized as a significant threat to agriculture, posing a serious challenge to global food security. The increasing earth’s surface temperature at an unprecedented rate is an alarming signal for meeting current and future global challenges. HTS mediated negative changes not only affect the health and economic condition of the Indian population but also influence global food security and create an imbalance in the carbon cycle. Therefore, it is necessary to understand the high-temperature mediated alterations in the developmental processes.
Professional & Academic Background
2023-Present
Scientist II, National Institute for Plant Genome Research (NIPGR)
2022-2023
Post-Doctoral Fellow, University of Wisconsin-Madison|OteguiLab,Wisconsin, USA
2020-2022
Post-Doctoral Fellow, Kansas State University, Kansas, USA
2013-2019
Ph.D. student, National Institute of Plant Genome Research, New Delhi, India
2011-2013
MSc-Lifesciences, School of Lifesciences, Jawaharlal Nehru University, New Delhi, India
2009-2011
B.Sc., Chhatrapati Shahu Ji Maharaj University, Kanpur, India
Awards & Honors
2023
Early Career Plant Scientist Travel Award and Oral Presentation in ASPB Plant Biology,Savanhh
2022-24
Early Career Representative (ECR),-American Society of Plant Biologist
2021-23
Assistant Feature Editor, Plant Physiology, ASPB
2023-24
Spotlight Editor, Physiologia Plantarum
2023-25
Early Career Professional Representative (ECLP), Genetics Society of America
2014, 2016
Best poster awardee at the prestigious proteomics international conferences, ‘PSI-2014’ and ‘PSIAOAPO-2016’ organized by the Proteomic Society of India
2013
Junior Research Fellowship and Lectureship in National Eligibility Test (NET) in Life Sciences, India
2013
Graduate Aptitude Test in Engineering (GATE), in Life Sciences, India.
Publications
Brahmam GS, Mishra D, Yadav VK* (2024). ReDtool: a Python-based command line tool for restriction digestion analysis of large DNA sequences. Journal of Plant Biochemistry and Biotechnology. 24:1-4. https://doi.org/10.1038/s41598-023-42420-7
Petersen M, Avin-Wittenberg T, Bassham DC, Dagdas Y, Fan C, Fernie AR , Jiang L, Mishra D, Otegui MS, Rodriguez E, Hofius D (2024) Autophagy in plants. Autophagy Rep 3:2395731. https://doi.
Mishra D#, Shekhar S#, Subba, P., Prasad, T.S.K., Chakraborty S, Chakraborty N (2024) Wheat TaNACa18 functions as a positive regulator of high-temperature adaptive responses and improves cell defense machinery. The Plant Journal (Accepted).https://doi.org/10.1111/tpj.16913
Mishra, D. (2024) Critical compromise: Trade-off between symbiosis and water uptake, Plant physiology, kiae264,https://doi.org/10.1093/plphys/kiae264
Mishra, D. (2024) Frost-fighter, SVALKA-PRC2: winter, bring it on! Plant physiology,https://doi.org/10.1093/plphys/kiae057
Mishra, D#. (2023) How pink is too pink: A tussle between plant and nature. Physiologia Plantarum,175(2), e13895,https://doi.org/10.1111/ppl.138952 (# corresponding author)
Mishra, D#. (2023) Closing the Loop: Three Musketeers of Autophagy-ATG2, ATG18a, and ATG9. Plant Physiology, 2022, kiac416https://academic.oup.com/plphys/advancearticle/doi/10.1093/plphys/kiad369/7209720(# corresponding author)
Mishra, D#. (2023) Off-putting! No red, no ripe: Methylglyoxal inhibits fruit ripening. Plant physiology, kiad239. https://doi.org/10.1093/plphys/kiad239(# corresponding author)
Mishra, D#. (2023) Hero or sidekick? Organellar reactive oxygen species during abscisic acid-induced stomatal closure, Plant Physiology kiad080, https://doi.org/10.1093/plphys/kiad080.(# corresponding author)
Pandey A, Sharma P, Mishra D*, Dey S, Malviya R, Gayen D. (2023) Genome-wide identification of the fibrillin gene family in chickpea (Cicer arietinum L.) and its response to drought stress. International Journal of Biological Macromolecules, 234, 123757.https://doi.org/10.1016/j.ijbiomac.2023.123757(* Co-first author)
Kaur, G.; Mishra, D#. (2022) AtABCG14: A Long-Distance Root-to-Shoot Carrier of Cytokinin. Int. J. Plant Biol., 13, 352-355. https://doi.org/10.3390/ijpb13030029 (# corresponding author)
Mishra, D# (2022) Take it easy in the heat: Transcription factors PIF4 and TCP4 interplay to slow leaf growth, Plant Physiology, kiac416,https://doi.org/10.1093/plphys/kiac416(# corresponding author)
Mishra, D# (2022) A big role for a microRNA in regulating cold tolerance and hormone signaling in rice, Plant Physiology, kiac292,https://doi.org/10.1093/plphys/kiac292(# corresponding author)
Mishra, D# (2022) How Stripe Rust Overcomes Wheat’s Defenses, Plant Physiology.kiac183,https://doi.org/10.1093/plphys/kiac183(# corresponding author)
Sharma, V.K., Marla, S., Zheng, W. Mishra, D., Huang, J., Zhang, W., Morris, GP., Cook DE. CRISPR guides induce gene silencing in plants in the absence of Cas. Genome Biol 23, 6 https://doi.org/10.1186/s13059-021-02586-7
Mishra, D., Shekhar, S., Chakraborty, S., Chakraborty, N. (2021). Wheat 2-Cys peroxiredoxin plays a dual role in chlorophyll biosynthesis and adaptation to high temperatures. Plant J. 105,1374-1389. https://onlinelibrary.wiley.com/doi/full/10.1111/tpj.15119
Mishra, D., Shekhar, S., Chakraborty, S., Chakraborty, N. (2021). High temperature stress responses and wheat: Impacts and alleviation strategies. Environmental and Experimental Botany, 190, 104589.https://doi.org/10.1016/j.envexpbot.2021.104589
Mishra, D., Suri, G.S., Kaur, G., Tiwari, M., (2021). Comprehensive analysis of structural, functional, and evolutionary dynamics of Leucine Rich Repeats-RLKs in Thinopyrum elongatum. International Journal of Biological Macromolecules,183, 513-527.https://doi.org/10.1016/j.ijbiomac.2021.04.137
Pareek A., Mishra, D., Shekhar, S., Chakraborty, S., & Chakraborty, N. (2021). The small heat shock proteins,chaperonin 10, in plants: An evolutionary view and emerging functional diversity. Environmental and Experimental Botany, 182, 0432. https://www.sciencedirect.com/science/article/pii/S009884722030349X
Alsaber, A, Al-Herz, A, Pan, J, AL-Sultan, AT, Mishra, D; KRRD Group. (2021). Handling missing data in a rheumatoid arthritis registry using random forest approach. International Journal of Rheumatic Diseases 24,1282-1293 https://doi.org/10.1111/1756-185X.14203
Mishra, D., Suri GS, Kaur G, Tiwari M. (2021). Comparative insight into the genomic landscape of SARS-CoV-2 and identification of mutations associated with the origin of infection and diversity. Journal of Medical Virology 93, 2406-2419. https://onlinelibrary.wiley.com/doi/10.1002/jmv.26744
Tiwari, M., and Mishra, D#. (2020) Investigating the genomic landscape of novel coronavirus (2019-nCoV) to identify non-synonymous mutations for use in diagnosis and drug design. Journal of Clinical Virology,128,1044. https://www.sciencedirect.com/science/article/pii/S1386653220301839.(#Co-first author and corresponding author)
Pareek A., Rathi D., Mishra D., Shekhar S., Chakraborty S., & Chakraborty N. (2019).Physiological plasticity to high temperature stress in chickpea: Adaptive responses and variable tolerance. Plant Sciences, 289, 110258. https://www.sciencedirect.com/science/article/pii/S0168945219308489
Mishra, D., Shekhar, S., Chakraborty, S., & Chakraborty, N. (2018). Carboxylate clamp tetratricopeptide repeat (TPR) domain containing Hsp90 cochaperones in Triticeace: An insight into structural and functional diversification. Environmental and Experimental Botany, 155, 31-44. https://www.sciencedirect.com/science/article/pii/S0098847218303939
Mishra, D., Shekhar S., Chakraborty S., Chakraborty N. (2017). Cultivar-specific high temperature stress responses in bread wheat (Triticum aestivum L.) associated withphysicochemical traits and defense pathways. Food Chemistry, 221, 1077-1087. https://www.sciencedirect.com/science/article/pii/S030881461631891X?via%3Dihub
Shekhar, S., Agrawal, L., Mishra, D., Buragohain, A. K., Unnikrishnan, M., Mohan, C., et al. (2016). Ectopic expression of amaranth seed storage albumin modulates photoassimilate transport and nutrient acquisition in sweetpotato. Scientific Reports, 6, 25384. https://www.nature.com/articles/srep25384
Shekhar, S., Mishra, D., Gayali, S., Buragohain, A. K., Chakraborty, S., & Chakraborty, N. (2016). Comparison of proteomic and metabolomic profiles of two contrasting ecotypes of sweetpotato (Ipomoea batata L.). Journal of Proteomics,143, 306-317. https://www.sciencedirect.com/science/article/pii/S1874391916300847?via%3Dihub
Shekhar, S., Mishra, D., Buragohain, A. K., Chakraborty, S., & Chakraborty, N. (2015).Comparative analysis of phytochemicals and nutrient availability in two contrasting sweet potato cultivars (Ipomoea batatas L.). Food Chemistry, 173, 957-965. https://www.sciencedirect.com/science/article/pii/S0308814614017014?via%3Dihub
Book Chapter
Mishra D., Shekhar S., Singh D., Chakraborty S., Chakraborty N. (2018) Heat Shock Proteins and Abiotic Stress Tolerance in Plants. In: Asea A., Kaur P. (eds) Regulation of Heat Shock Protein Responses. Heat Shock Proteins, vol 13. Springer, Cham. https://www.springer.com/gp/book/9783319747149
Mishra, D., Suri GS, Kaur G, Mehta S, Singh B, Tiwari M (2021). Genomic Evidence Provides the Understanding of SARS-CoV-2 Composition, Divergence, and Diagnosis. Integrated Omics Approaches Infectious Diseases, 542, Springer Nature.https://link.springer.com/chapter/10.1007/978-981-16-0691-5_4
Editorial experience
Academic Editor, Plant Direct.
Editorial Board Member, Crop Design, Elsevier.
Early Career Reviewer, The Journal of Biological Chemistry.
Review editor, Frontiers in plant sciences and pharmaceutical innovations.
Reviewer Board Member, Microorganisms.