Professional and Academic Background
- Staff Scientist II (Jan 2017- present): National Institute of Plant Genome Research
- SERB-DST Young Scientist (2016 - 2017): University of Delhi South Campus
- Post-doctoral Fellow (2014-2015): Washington State University, Pullman, USA.
- Ph.D. (2008-2014): Department of Plant Molecular Biology, University of Delhi South Campus.
- M.Sc. (2005-2007): Jamia Millia Islamia, New Delhi.
- B.Sc. (2002-2005): Hansraj College, University of Delhi
Awards & Honors
- Pran Vohra Award - 2018-19 from Indian Science Congress Association (ISCA).
- Young Scientist Platinum Jubilee Award (2017) from the National Academy of Sciences, India (NASI).
- SERB-DST Young Scientist Award, 2015, Department of Science and Technology, Govt. of India
- Young Investigator Award from RCB, 2015, Department of Biotechnology, Govt. of India (not availed)
- Dr. D.S. Kothari Post-doctoral Fellowship, 2015, (higher fellowship, not availed)
- Ph.D. Young Scientist Travel Award, 2012, from American Society of Plant Biologists (ASPB), USA
- Ph.D. student Foreign Travel Award, 2012, from Council of Scientific and Industrial Research (CSIR)
- Membership of American Society of Plant Biologists (2014-2015).
- Reviewer for international research journals including PLoS ONE, Plant Molecular Biology Reporter, Journal of Plant Biochemistry and Biotechnology and Acta Physiologiae Plantarum.
- Junior and Senior Research Fellowship, 2008-2013 from CSIR, India.
Research Interests
Abiotic stresses such as drought and salinity hampers crop production and impose the problem of food security. Therefore, to combat the problem, there is need to develop the stress tolerant and high yielding crop varieties. Tolerance or susceptibility to abiotic stresses in plants is conferred by coordinated function of various genes, including those encoding enzymes such as kinases, phosphatases, phospholipases, transcription factors and transporters/channel proteins. Our group is interested in understanding molecular character and functional behavior of these key signaling components through, bioinformatics, molecular, cellular, biochemical and genetic approaches to dissect the signaling networks underlying abiotic stress adaptive mechanism in vital crop plant, rice (Oryza sativa).
Potassium (K+) deficiency adversely affects plant growth and development because K+ is required as a macronutrient in vital cellular processes such as metabolism, growth, enzyme activation, osmoregulation, and maintenance of membrane potential. Various abnormalities in plant growth and development under low-K+ conditions occur due to inhibition of essential biochemical and physiological events such as protein synthesis and photosynthesis. In order to counteract and adapt to K+ deficient environment it's inevitable to maintain cellular K+ homeostasis through efficient uptake and transport across different membranes. The K+ deficiency signaling and responses have been studied in model plant Arabidopsis but the knowledge is miniscule in important food crops. Therefore, our other major focus is to undertake a comprehensive functional study to understand K+ deficiency signaling and adaptive responses in crucial legume crop chick pea (Cicer arietinum) .
Group Members
- Sushma Sagar Ph.D. Student
- Komal Vitthalrao Mali Ph.D. Student
- Deepika Ph.D. Student
- Dipul Kumar Biswas Senior Research fellow (SRF)
- Amit Kumar Junior Research fellow (JRF)
Selected Publications
- Singh A, Yadav AK, Kaur K, Sanyal SK, Jha SK, Fernandes JL, Sharma P, Tokas I, Pandey A, Luan S, Pandey GK (2018) Protein Phosphatase 2C, AP2C1 Interacts with and Negatively Regulates the Function of CIPK9 under Potassium Deficient Conditions in Arabidopsis. Journal of Experimental Botany. DOI: https://doi.org/10.1093/jxb/ery182
- Sagar S and Singh A* (2018) Abscisic acid, a principal regulator of plant abiotic stress responses. In: Khan I, Reddy SP, Ferrante A, Khan NS (eds). Plant Signaling Molecules: Role and Regulation under Stressful Environments, Elsevier Publishers, USA. (In Press)
- Singh A, Sagar S, Biswas DK (2018) Calcium Dependent Protein Kinase, a Versatile Player in Plant Stress Management and Development. Critical Reviews in Plant Sciences, DOI: 10.1080/07352689.2018.1428438
- Singh A, Pandey A, Srivastava AK, Tran LSP, Pandey GK (2016) Plant protein phosphatase 2C: from genomic diversity to functional multiplicity and importance in stress management. Critical Reviews in Biotechnology.36(6): 1023–1035
- Singh A, Pandey GK (2016) How Phospholipase C regulates stress tolerance and development in plants? Journal of Cell Signaling.1:132
- Singh A, Pandey GK (2016) Phospholipase C break membrane lipids during plant adaptation under stress. Atlas of Science, 12 May.
- Singh A, Jha SK, Bagri J, Pandey GK (2015) ABA inducible rice protein phosphatase 2C confers ABA insensitivity and abiotic stress tolerance in Arabidopsis.PLoS ONE.10(4), e0125168.
- Singh A, Bhatnagar N, Pandey A, Pandey GK (2015) Plant phospholipase C family: regulation and functional role in lipid signaling. Cell Calcium. 58(2):139-46 .
- Pandey GK, Kanwar P, Singh A, Steinhorst L, Pandey A, Yadav AK, Tokas I,Sanyal S, Lee SC, Cheong YH, Kudla J, Luan S. (2015) CBL-interacting protein kinase, CIPK21, regulates osmotic and salt stress responses in Arabidopsis. Plant Physiology.169:780-792
- Singh A and Pandey GK. (2015) Primer Design using Primer Express® for SYBR Green based Quantitative PCR. Methods Molecular Biology. 1275:153-164, Springer Science + Business Media New York, ed. Chhandak Basu.
- Zeng H, Xu L, Singh A, Wang H, Du L, Poovaiah BW (2015) Involvement of Calmodulin and Calmodulin-like Proteins in Plant Response to Environmental Stress. Frontiers in Plant Science.6:600
- Singh A, Kanwar P, Yadav AK, Mishra M, Baranwal V, Pandey A, Kapoor S, Tyagi AK, Pandey GK (2014) Genome-wide expressional and functional analysis of calcium transport elements during abiotic stress and development in rice. FEBS Journal. 281:894-915
- Sharma M, Singh A, Shankar A, Pandey A, Baranwal V, Kapoor S,Tyagi AK, Pandey GK (2014) Comprehensive Expression Analysis of Rice Armadillo Gene Family During Abiotic Stress and Development. DNA Research.21(3): 267-283
- Singh A, Kanwar P, Pandey A, Tyagi AK, Sopory SK, Kapoor S, Pandey GK (2013) Comprehensive Genomic Analysis and Expression Profiling of Phospholipase C gene family during Abiotic Stress and Development in Rice. PLoS ONE. 8(4):e62494
- Shankar A, Singh A, Kanwar P, Srivastava AK, Pandey A, Suprasanna P, Kapoor S, Pandey GK (2013) Gene expression analysis of rice seedling under potassium deprivation reveals major changes in metabolism and signaling components. PLoS ONE. 8(7): e70321
- Mishra M, Kanwar P, Singh A, Pandey A, Kapoor S, Pandey GK (2013) Genome-wide Analysis of ABA Repressor1 (ABR1) Related Genes in Rice During Abiotic Stress and Development. Plant OMICS.17(8): 439-450
- Singh A, Baranwal V, Shankar A, Kanwar P, Ranjan R, Yadav S, Pandey A, Kapoor S, Pandey GK (2012) Rice phospholipase A superfamily: organization, phylogenetic and expression analysis during abiotic stresses and development. PLoS ONE.7(2): e30947
- Singh A, Pandey A, Pandey GK (2012) Phospholipase D in stress activated lipid signaling in plants. Global Science Books. Plant Stress 6 (Special Issue 1):10-17. Global Science Books, Japan, ed, Jaime A. Teixeira da Silva. Cover page model
- Singh A, Pandey A, Baranwal V, Kapoor S, Pandey GK (2012) Comprehensive Expression Analysis of Rice Phospholipase D Gene Family during Abiotic Stresses and Development. Plant Signaling & Behavior. 7(7): 847-855
- Singh A, Pandey GK (2012) Protein phosphatases: A genomic outlook to understand the function in plants. Journal of Plant Biochemistry Biotechnology. 21(1 supplement):100-107
- Singh A, Giri J, Kapoor S, Tyagi AK, Pandey GK (2010) Protein phosphatase complement in rice: genome-wide identification and transcriptional analysis under abiotic stress conditions and reproductive development. BMC Genomics. 11:435. highly accessed article.