NEXCADE

STEP WISE ASSISTANCE TUTORIAL

BROWSE NEXCADE PRECOMPUTED RESULTS ON SELECT DATASETS

For direct access to NEXCADE precomputed scans, click on 'Browse Webs' link in the menu bar on any page, as follows:

Browse Webs Page

Users can select the dataset type or the system of interest from among twelve different pre-scanned networks as shown above.

Each network can be accessed by clicking on the network name.

We have included diverse networks for this section of the server, including protein-protein interaction data, genetic interaction data, co-expression data, bipartite ecological webs of interactions between organisms, and social network data.

On clicking a network of interest, the first page provides a brief summary of the network and its source. (For more details and full references, please see text of our paper)

Here are a few examples:

Example Network 1

On each of these summary pages, a link has been provided to view NEXCADE output for that network, as follows:

Browse Example Results

On clicking this link, the main results window can be seen, as follows:

Example Result Page

As can be seen above, the output of the NEXCADE scan results is divided into four major sections for analysis of a given network, namely:

(I) Visualization and Attributes

(II) Simulation of Single Perturbations

(III) Simulation of Grouped Perturbations and

(IV) Simulation of Serial or Cascading Perturbations,
each of which enables users to carry out desired simulations and impact analysis.

For more details and a step wise tutorial through any of these sections, click the respective links below.

Visualization and Attributes

Simulation of Single Perturbations

Simulation of Grouped Perturbations

Simulation of Sequential Perturbations