Nexcade is an automated and interactive program for analysing complex systems that can be conceptualized by networks, and represented as interconnected matrices of interactions. The analytical framework employs a graph theoretical approach for inducing various kinds of perturbations on networks such as extinction cascade simulations, focusing on the changes in topology and connectivity of the network as a function of the perturbation. Perturbations are induced in a user-defined manner followed by analysis of the resulting sub-networks.