Food Security Initiative

As part of the DBT-Cambridge Lectureship program, I am trying to explore the connection between photosynthetic efficiency and epigenetic inheritance. This is being investigated through comparative analysis of Carbon concentrating mechanisms in model plants and green algae, using available leaf DNAse sequence datasets for select C3/C4 species, as well as various light and dark stage transcriptomes along the Chlamydomonas diurnal cycle. (Work Funded by the RCUK)

Data Science & Complex Networks

Recognising that biological networks are complex systems, vulnerable to attacks or failure, we have gained insights into network resilience and susceptibility through induction of a variety of random and targeted perturbations in hundreds of biological networks, followed by investigation of their responses under attack. This has enabled us to develop tools for predicting robustness in real world networks. We are also constructing species specific GRNs for selected gene families such as the Star-related lipid transfer domains, Histone-fold motif and KIX, in order to understand functional diversification during evolution. (Work Funded by DBT-BTISNET)

Computational Ecology

Our focus is on plant communication mediated by phytochemicals, using knowledge based Big Data approaches like genomics, Geo-spatial imaging and species distribution modeling. We are particularly interested in exploring the role played by volatile organic compounds in mediating biological invasions by alien plant species, better known as the 'Novel Weapons Hypothesis'. In collaboration with field ecologists, we are approaching invasion biology from a genomics standpoint, wherein we compare Phytochemical dynamics within and across habitats, in order to build models for understanding invasion success at both above-ground and plant-soil interaction level. (Work Funded by SERB/DST)

• INSA Bilateral Exchange Program Award (2018) by Indian National Science Academy
• Hamied Fellowship Award (2017) by the University of Cambridge, UK
• Early Career Award Selection for CSC-2017 by the Royal Society of London, UK
• Member of the British Ecological Society (2017), UK
• DBT-Cambridge Lectureship (2016), joint Award by DBT and Cambridge University, UK
• Member of the National Academy of Sciences India (NASI), 2016
• Life Member of the Indian Society for Plant Physiologists (ISPP)
• Member of the Indian National Young Academy of Science (INYAS): 2016 - 2021
• SERB ' Women Excellence Award' (2013) by Science and Engineering Research Board (SERB), India.
• Haryana Yuva Vigyan Ratna Award (2010-11) by the Haryana State HSCST. Covered By The Hindu
• INSA Medal for Young Scientists (2011) [Biochemistry & Biophysics] by the Indian National Science Academy.
• Associate of the Indian Academy of Sciences (2010-2014).
• Prof. Hira Lal Chakravarty memorial award in Plant Sciences (2010) - by the ISCA (Indian Science Association).
• Senior IYBA Award, DBT, India - 2009.
• Young Scientist Platinum Jubilee Award (2009) from the National Academy of Sciences India (NASI).
• Innovative Young Biotechnologist Award (IYBA), DBT, India - 2005.
• Visiting Scientist at The Keck Graduate Institute, Claremont, CA, USA (2006).
• Junior and Senior Research Fellowships from CSIR, Govt of India (2000 and 2002).
• 'Catch Them Young' Fellowship from CSIR (1998-2000)

• Member, COVID Projects Steering Committee, NCSTC -DST, Govt of India (2020 onwards)
• Member, Advisory Board, Hyderabad City Cluster, Telangana Government
• Member, Delhi City Knowledge Education Cluster
• Member, Expert Committee for Implementation of Programmes for Accelerated Participation of Women in Science and Technology, DST, Govt of India
• Member of Ramalingswami Awards Selection Committee, Dept of Biotechnology Govt of India (2017-onwards)
• Member OC, INYAS-National Frontiers of Science (NatFoS) Meeting - 2020
• Development of India-U.K Crop Science Fellowship with DBT & eight U.K partners (2020)
• Launch Declaration: Code of Conduct for Young Academies with Global Young Academy (2019)
• Member, ASEAN SIT Panel for Biotechnology and Life Sciences (2020 -2023)
• Organised Launch of Cambridge India Research Foundation (CIRF) Jan 2019, New Delhi
• Action Plan on Policies for Secure & Sustainable Agriculture in India (2019)
• Frameworks for research policy at Anglo Israeli Roundtable in London (2019)
• India-U.K Round Table on  “Fostering Entrepreneurial Innovation in Agri Tech”, New Delhi (2019)"
• Project Task Force Panels: Inno-China (2019) , INYAS-NatFoS (2018-20), DBT-CTEP (2014-17)

• Babu, S and Yadav G* (2018) Robustness through Regime Flips in Collapsing Ecological Networks. Studies in Computational Intelligence Series. Eds Kacprzyk, Janusz. ISSN: 1860-949X (Springer-Verlag).
• Babu, S and Yadav G* (2018) Extinction Curves and Error Propagation in Mutualistic Ecological Networks: The Case of Frugivores in a Tropical Rainforest. In Proceedings of the 7th International Conference on Complex Networks and Their Applications. December 11-13, 2018, Cambridge, United Kingdom.
• Priya P, Yadav A, Jyoti C and Yadav G* (2018)  TERZYME: A Tool for Quantification and Analysis of the plant Terpenome. Plant Methods (In Press)
• Yadav A, Thakur JK and  Yadav G* (2017)  KIXBASE: A Comprehensive web resource for identification and exploration of KIX domains. Scientific Reports 7(1):14924.
• Yadav G and Mohanty, D (2017) Databases developed in India for Biological Sciences. Journal of Proteins and Proteomics 8(3), 159-167
• Patra B, Kon Y, Yadav G, Sevold A,.. Hintze A, Galas D and Ray A* (2017) A genome wide dosage suppressor network reveals genetic robustness Nucleic Acids Research 45(1),255–270
• Priya P, Kumari S and Yadav G* (2016) Quantification of the plant terpenome: predicted versus actual emission potentials. Ind J Plant Phys DOI: 10.1007/s40502-016-0256-x
• Yadav G* and Babu S (2016) Evidence for alternate stable states in collapsing ecological networks. doi: Biorxiv/2016/046045
• Amish K and Yadav G* (2016) Diversification of the Histone Fold Motif (HFM) in Plants: Evolution of New Functional Roles. Journal of Life Sciences (In Press)
• Babu S and Yadav G* (2016) Life Science Co-Authorship Networks Reveal Patterns of Scientific Collaboration and Research Impact. Journal of Life Sciences (In Press)
• Priya P, Bandhiwal N, Misra G, Mondal S and Yadav G* (2015) IGMAP: An Interactive Mapping and Clustering Platform for Plants. Molecular Plant. 8(5): 818–821. doi:10.1016/j.molp.2015.01.018
• Parween S, Nawaz K, Roy R, Pole AK, Venkata Suresh B, Misra G, Jain M, Yadav G, Parida SK, Tyagi AK, Bhatia S, Chattopadhyay D (2015) An advanced draft genome assembly of a desi type chickpea (Cicer arietinum L.). Scientific Reports Doi: 10.1038/srep12806.
• Yadav M., Babu S. and Yadav G* (2015) Patterns of Codon Usage in Plastidial Genomes of Ancient Plants Provide Insights into Evolution. In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms, pages 144-149. DOI: 10.5220/0005246301440149
• Kumari S, Pundhir S, Priya P, Jeena G, Punetha A, Chawla K, Jafaree Z, Mondal S and Yadav G* (2014) EssOilDB: A Database of Essential Oils reflecting Terpene Composition and Variability in the Plant Kingdom. Database DOI: 10.1093/database/bau120
• Misra G, Priya P, Bandhiwal N, Bareja N, Jain M, Bhatia S, Chattopadhyay D, Tyagi AK and Yadav G* (2014) The Chickpea Genomic Web Resource: Visualization and Analysis of the Desi-type Cicer arietinum Nuclear Genome for Comparative Exploration of Legumes. BMC Plant Biology. 14(1): 315
• [Recommended by Faculty of 1000] Schrick K, Bruno M, Khosla A, Roque RA, Nguyen H, Snyder MP, Singh D and Yadav G (2014) Shared functions of plant and mammalian StAR-related lipid transfer (START) domains in modulating transcription factor activity. BMC Biology. 12:70 doi:10.1186/s12915-014-0070-8 ( View Recommendation Here)
• Thakur JK, Yadav A and Yadav G* (2014) Molecular recognition by the KIX domain and its role in gene regulation. Nucl. Acids Res. 42 (4): 2112-2125
• Kumari S, Priya P, Misra G and Yadav G* (2013) Structural and biochemical perspectives in plant isoprenoid biosynthesis. Phytochemistry Reviews. 12: 255-291
• Jain M, Misra G, Patel RK, Priya P, Jhanwar S, Khan AW, Shah N, Singh VK, Garg R, Jeena G, Yadav M, Kant C, Sharma P, Yadav G, Bhatia S, Tyagi AK, Chattopadhyay D (2013) A draft genome sequence of the pulse crop chickpea (Cicer arietinum L.). Plant Journal. DOI: 10.1111/tpj.12173
• Kumari R, Yadav G, Sharma V & Kumar S (2013) Cytosine hypomethylation at CHG and CHH sites in the pleiotropic mutants of Mendelian inheritance in Catharanthus roseus. Journal of Genetics 92(3): 499-511
• Kumar S, Kumari R, Sharma V & Yadav G (2013) Common and Distinguishing Characteristics of Genes and Genomes and Their Evolution in the Genome Sequenced Legumes. Proc Indian Natl Sci Acad. 79 (2): 277-286
• Yadav G, Anand S and Mohanty D (2013) Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis. Journal of Biomolecular Structure and Dynamics 31(1): 17-29. (Spl Issue: Predictive biology using systems and integrative analysis and methods)
• Yadav G* and Babu S (2012) NEXCADE: Perturbation Analysis for Complex Networks. PLoS ONE 7(8): e41827. doi:10.1371/journal.pone.0041827
• Kumari S, Shridhar S, Singh D, Farmer R, Hundal J, Priya P, Sharma P, Bhavishi K, Schrick K, and Yadav G*. (2012) The role of lectins and HD-ZIP transcription factors in Isoprenoid based plant stress responses Proc. Ind. Natl. Sci. Acad. 78 (4): 671-691 (Article in Cover Illustration)
• Gaur R, Azam S, Jeena G, Khan AW, Chaudhary S, Jain M, Yadav G, Tyagi AK, Chattopadhyay D, Bhatia S (2012) High-throughput SNP discovery and genotyping for constructing a saturated linkage map of chickpea (Cicer arietinum L.). DNA Research pp:1-17 doi:10.1093/dnares/dss018
• Chaudhary S, Sharma V, Prasad M, Bhatia S, Tripathi BN, Yadav G, Kumar S (2011) Characterization and genetic linkage mapping of the horticulturally important mutation leafless inflorescence (lli) in periwinkle Catharanthus roseus. Sci. Horti. (in press) Doi: 10.1016/j.scienta.2011.02.025
• Garg R, Patel RK, Jhanwar S, Priya P, Bhattacharjee A, Yadav G, Bhatia S et al (2011) Gene discovery and tissue-specific transcriptome analysis in chickpea with massively parallel pyrosequencing and web resource development. Plant Physiol 156: 1661-1678.
• Anand S, Prasad MV, Yadav G, Kumar N, Shehara J et al.(2010) SBSPKS: structure based sequence analysis of polyketide synthases. Nucl. Acids. Res. 2010 May 5. [Epub ahead of print]
• Shridhar S, Chattopadhyay D and Yadav G* (2009) PLecDom: A program for identification and analysis of plant Lectin Domains. Nucl. Acids. Res. Jul 1;37: W452-8. Epub 2009 May 27.
• Kumar S, Mishra RK, Chaudhary S, Pandey R and Yadav G (2009) Co-regulation of Biomass Partitioning by Leafblade Morphology Genes Afila, Multifoliate-pinna, Tendril-less and Unifoliata in Grain Pea Pisum sativum. Proc. Ind. Natl. Sc. Acad, 75 No. 1 pp 15-25.
• Yadav G, Gokhale RS and Mohanty D (2009) Towards prediction of metabolic products of Polyketide Synthases: An In Silico analysis. PLoS. Comp. Biol. Apr; Vol 5(4): e1000351.
• Yadav G*, Prasad RLA, Jha BK, Rai V, Bhakuni VK and Datta K (2008). Evidence for inhibitory interaction of hyaluronan binding protein 1 (HABP1/p32/gC1qR) with S. pneumoniae hyaluronidase. J. Biol. Chem 284(6): 3897-3905 (*corresponding authors)
• Kaur H, Shukla RK, Yadav G, Chattopadhyay D and Majee M (2008) Two divergent genes encoding L-myo-inositol 1 -phosphate synthase1 (CaMIPS1) and 2 (CaMIPS2) are differentially expressed in chickpea. Plant, Cell and Environment 31: 1701-1716.
• Chopra T, Banerjee S, Gupta S, Yadav G, Anand S, et al. (2008) Novel Intermolecular Iterative Mechanism for Biosynthesis of Mycoketide Catalyzed by a Bimodular Polyketide Synthase. PLoS Biology 6(7): e163 doi:10.1371/journal.pbio.0060163.
• Ansari MZ, Yadav G, Gokhale RS and Mohanty D (2004) NRPS-PKS A knowledge based resource for analysis of non-ribosomal peptide synthetases and polyketide synthases. Nucl. Acids Res. 32: W401-W415.
• Yadav G, Gokhale RS and Mohanty D (2003) Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases. J. Mol. Biol. 328: 335-63.
• Yadav G, Gokhale RS and Mohanty D (2003) SEARCHPKS: A Program for detection and analysis of polyketide synthase domains. Nucl. Acids Res. 31: 3654-3658.
• Saxena P, Yadav G, Mohanty D and Gokhale RS (2003) A new family of type III polyketide synthases in Mycobacterium tuberculosis. J. Biol. Chem. 278: 44780-90.
• Yadav G, Gokhale RS and Mohanty D (2004) Protein Science, 13 (1): 185, PS-04; 18th Synposium of the Protein Society, San Diego, California, August 14-18, 2004.
• Yadav G, Gokhale RS and Mohanty D (2003) Abstract P9-01, 10th FAOBMB Congress Bangalore (India), Abstracts from International Conference.
• Yadav G and Mohanty D (2001) Abstracts of the International Symposium on Crystallography and Bioinformatics in Structural Biology. S9